Dyslipidemia is one of the most common problems in the world population, caused mainly by bad eating habits . 

In this sense, medical science, concerned about the high rates of morbidity and mortality due to this disorder, has created, in collaboration with the drug industry, drugs to regulate blood lipid levels, including bezafibrate.

In this article, we explain what bezafibrate is and for what circumstances your doctor can prescribe it.

What is bezafibrate?

Bezafibrate is a synthetically manufactured medication used to treat patients with metabolic disorders caused by conditions such as obesity or diabetes mellitus.

Its active ingredient is bezafibrate, a drug belonging to the lipid-lowering group, which exerts its action mainly on the metabolism of lipoproteins rich in triglycerides, blocking lipolysis of adipose tissue and reducing the concentration of fatty acids in the blood. (1)

Important: By reducing the values ​​of VLDL low-density lipoproteins, the concentration of high-density cholesterol (HDL) in the blood increases.

On the other hand, the commercial presentation of this medicine is in 200 mg immediate release tablets. Its route of administration is oral and the recommended dose is 1 tablet 3 times a day . In cases of hypertriglyceridemia, if the response to treatment is favourable, the dose can be reduced to one tablet twice a day.

What is bezafibrate used for?

This drug is indicated to regulate high levels of triglycerides and cholesterol, especially characterized in those patients with states of hypertriglyceridemia (type IIb, III, IV and V dyslipidemia) or with an altered lipid profile.

To highlight: A scientific article proposes the use of lipid-lowering agents such as bezafibrate for the treatment of dyslipidemia. (two)

Bezafibrate Side Effects

This medication may cause some of the following side effects in certain patients:

  • Allergic reactions due to contact with some of the components of this medicine.
  • Loss of appetite, feeling of fullness in the stomach, and nausea may occur.
  • Although there are no studies to confirm it, bezafibrate may increase the risk of cholelithiasis (formation of stones in the gallbladder).
  • It can potentiate the action of insulin.

You should know: Tell your doctor if you notice the appearance of any of these symptoms or another not included in the list and try to receive all the information about this drug before starting treatment.

Contraindications of bezafibrate

Treatment with bezafibrate is contraindicated in any of the following cases:

  • Hypersensitivity to any of the components of bezafibrate.
  • In patients with diseases of the gallbladder.
  • In people suffering from kidney failure.
  • In patients with liver diseases, with the exception of fatty liver.
  • It should not be administered during pregnancy or while breastfeeding.
  • Avoid consuming this medicine if you are receiving dialysis treatment, without having results on blood creatinine levels.

Important: Before starting a treatment with this medicine, it is advisable to review your specialist medical history .

Key Findings

  • Bezafibrate is a synthetic medication, used for the treatment of patients with metabolic disorders .
  • Its active principle is bezafibrate, a chemical compound that exerts its action on the metabolism of lipoproteins rich in triglycerides.
  • Bezafibrate works by regulating high triglyceride and cholesterol levels, especially in patients with states of hypertriglyceridemia.
  • This medicine must be prescribed by a specialist doctor.

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