Nimesulide: What is it and what is it for?

What is nimesulide?

Nimesulideis a synthetic drug, classified as an active ingredientwith analgesic, antipyretic and anti-inflammatory properties for the relief of certain discomforts in the body. (1)

What is nimesulide for?

• Nimesulide is mainly a non-steroidalanti-inflammatory drug, with analgesic and antipyretic properties, indicated in the treatment for therelief of pain, inflammation and fever caused by various reasons.
• It is used to treat:
  • Primary dysmenorrhea.
  • Pain caused after surgery.
  • Cystitis, pharyngitis, sore throat and headache.
  • Otitis.
  • Tendinitis.
  • Joint pain. (2)

Dosage and routes of administration of nimesulide

Nimesulide usually comes asa 100 mg tablet, but it is also sold in drops, suppositories, or ointment. The route of administration for tabletsand drops is oral and the dose for informational purposes may be as follows:

• Adults: You can take1 or 2 tablets every 12 hours, as recommended by the attending physician.
• Older adults : 1 tablet every 12 hours without increasing the dose and under medical supervision .

What products contain nimesulide?

Some of the medicines that contain nimesulide are:

• Aulin®
• Scaflan®
• Scaflogin®
• Guaxan®

Aulin®

• Aulin® is the trademark of a synthetic medicine, which contains nimesulide in 100 mg tablets.
• It is indicated for the short-term symptomatic treatment of painful inflammatory states.

Scaflan®

• Scaflan® is a medicine with anti- inflammatory, analgesic and antipyretic properties, which uses nimesulide as the active ingredient.
• It is indicated in the treatment of inflammatory symptoms in patients with osteoarthritis and rheumatic diseases for the relief of acute pain.

Scaflogin®

• Scaflogin® is a synthetic drug that contains nimesulide as the active ingredient in 100 mg tablets.
• It is indicated for a variety of conditions that require anti-inflammatory, analgesic, and antipyretic activity..

Guaxan®

• Guaxan® is available as tablets, which contain 100 mg of the active substance nimesulide.
• It is indicated for the treatment of acute pain,and menstrual cramps.

Nimesulide Side Effects

The administration of nimesulide can cause in certain patients some of the following adverse effects. in certain patients.

• Allergic reactions due to contact with any component of the formula.
• May cause Vomiting and diarrhea .
• Drowsiness and vertigo.
• It can produce the risk of intestinal bleeding.
• May cause additive effects with concomitant use with acetylsalicylic acid .
• Arterial hypertension.
• Possible skin rash.
• An ocular type disorder may occur.

Important: If during treatment with nimesulide you notice the appearance of any of these symptoms or another not included in the list, stop using it and consult your doctor.

Contraindications and warnings of nimesulide

Treatment with nimesulide is contraindicated in the following cases:

• Hypersensitivity to any of the formula’s components.
• In patients suffering from alcoholism or hepatitis.
• It should not be administered to children under 12 years of age.
• Do not administer during pregnancy or lactation .

You should know: Before starting treatment with nimesulide, provide all the Information relatedto your health historyyour doctor.

Avoid if you have:

• That drive or operate machinery.
• Hepatic or renal failure.
• Cardiovascular problems.
• Gastrointestinal bleeding.
• Peptic ulcer .
• Medication with acetylsalicylic acid.
• Hypersensitivity to non-steroidal anti-inflammatory drugs.
• Some systemic disease such as cytopenia.

Warnings:

• It is recommended to take this medicine after food.
• When administered to older adults, constant monitoring is recommended.
• It should be administered with caution, in patients suffering from intestinal constipation.
• This medicine is for delicate use, so its administration must be with a medical prescription.
• Do not consume this medicine after the expiration date.
• Keep stored in a dry and cool place.
• Drugs such as nimesulide should be kept out of the reach of children.
• Simultaneous administration of lithium with this drug may cause an increase in plasma lithium.