What is nalixone?
Nalixone® is the registered trademark of a pharmaceutically manufactured medicine that uses nalidixic acid (1) and phenazopyridine as active ingredients , two chemical substances belonging to the line of medicines with local antibiotic and analgesic effect, with action on certain urinary infections . caused by bacteria .
To highlight: This pharmaceutical product is made by the company called Laboratorios Química Son’s CA de CV (2)
What is nalixone used for?
- Thanks to the joint action mechanism of its active ingredients, nalixone® has a bactericidal property to eliminate a large number of bacterial microorganisms, in addition to having a local analgesic effect to relieve ailments caused by an infection in the urinary tract.
- It is used to treat:
- Acute and painful urinary tract infections caused by gram- negative microorganisms sensitive to nalidixic acid and associated symptoms ( Klebsiella, Enterobacter, Escherichia coli and most Proteus strains ). (3)
Dosage and routes of administration of nalixone
Nalixone® is sold in a box with 20 tablets, where each tablet contains nalidixic acid 500 mg, 50 mg of phenazopyridine hydrochloride. The administration is orally and the dosage as a reference can be as follows:
- Adults: Dose of 2 tablets every 6 hours per day.
- Children: Dose of 55 mg/kg of weight per day or 1.5 to 2 g per day, in several doses.
side effects of nalixone
Therapeutic treatment with nalixone® may cause some of the following adverse reactions in a certain patient population:
- Possible allergic reactions in patients sensitive to the components of the formula.
- Itching, hives and angioedema.
- Eosinophilia, joint stiffness.
- Toxic psychoses or mild seizures.
- Drowsiness, weakness, headache, paresthesias and vertigo.
- Subjective and reversible visual disturbances.
- Photosensitivity and change in color perception.
- Increased intracranial pressure, with bulging of the anterior fontanelle.
- Dyspepsia, abdominal pain , nausea, vomiting and diarrhea .
- Leukopenia or hemolytic anemia .
Important: If any of these symptoms appear or another that is not included in the list, please stop its consumption and consult your doctor .
Contraindications and warnings of nalixone
The use of nalixone® is contraindicated in the following cases:
- Patient hypersensitivity to any of the components of the formula or antibiotics from the quinolone group.
- Patients with kidney failure.
- Liver failure.
- In children under 1 year of age.
- During the first trimester of pregnancy.
- During the breastfeeding period .
You should know: Before starting treatment with this drug, provide all the information regarding your health history to your doctor.
Avoid if you have:
- History of hypersensitivity to the components of the formula or to quinolones.
- History of seizures.
- History of severe kidney or liver damage.
- Products such as nalixone® must be administered with a prescription or prescription.
- Follow your doctor’s instructions during treatment with this drug.
- This product must be administered under medical supervision.
- Nalidixic acid may increase the effects of oral anticoagulants.
- Keep this medicine out of the reach of children.
University Professional in the area of Human Resources, Postgraduate in Occupational Health and Hygiene of the Work Environment, 14 years of experience in the area of health. Interested in topics of Psychology, Occupational Health, and General Medicine.