What is loperamide?

Loperamide is a synthetically manufactured drug, which is used by outpatient medicine in some cases of gastrointestinal disorders in humans and belongs to a class of medications called antidiarrheal agents.

Its active ingredient is loperamide, a chemical compound that is used to control disorders of the stomach and digestive tract due to the presence of bacteria, viruses and parasites, as well as pathologies associated with inflammatory bowel disease.

Note: The mechanism of action of this drug is based on thereduction of motilityand the secretion of fluids and electrolytes, in addition to increasing the absorption of water.

It should be noted that the commercial presentations of this drug are in solution,tablets or capsules of 2 mg, whose recommended dose is 4 mg orally after the first evacuation and continue with a dose of 2 mg after each evacuation if they persist. The maximum dose in adults is 2 mg three times a day and in children 1 mg 3 times a day.

What is loperamide for?

in adults and children 6 years of age and older. In the case of ileostomies, to reduce the volume and number of stools.

and , therefore reducing propulsive peristalsis, increasing intestinal transit time and favoring the process of fluid reabsorption.

To highlight: This medicine must be administered with a prescription and with constant supervision .

Loperamide Side Effects

The consumption of medications has its risks in some patients , so the use of loperamide can cause any of the following adverse effects:

  • Allergic reactions to the chemical components of loperamide.
  • Central nervous system depression .
  • In the elderly, the risk of urinary retention may increase.
  • Abdominal distention, asthenia, dizziness and skin rashes.
  • Constipation.

Important: If you observe the appearance of any of these adverse reactions or any other effect not included in the list, it is recommended to discontinue its use immediately and consult the treating physician .

Contraindications of loperamide

Medications may have contraindications for some people due to the health conditions of each patient, therefore the use of loperamide is not recommended in the following situations:

  • If there is hypersensitivity to any of the chemical components of loperamide.
  • In patients with hepatic insufficiency.
  • Use in women during pregnancy or breastfeeding is not recommended, as there are not enough studies in this field.
  • In children under 2 years of age.

You should know: For greater safety in the use of loperamide , the patient should provide his doctor with all possible information regarding his medical history.

Key Conclusions

  • Loperamide is a synthetic drug that belongs to the group of inhibitors of intestinal motility.
  • Loperamide is indicated to treat acute nonspecific diarrhea and chronic diarrhea.
  • This medication inhibits the secretion of acetylcholine and prostaglandins, thus reducing propulsive peristalsis.
  • Loperamide must be prescribed by a doctor after evaluation and follow-up.

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