What is clexane and what is it for?

Diseases that affect the circulatory and cardiac system can become harmful if they are not treated properly, since they correspond to a series of conditions that usually directly affect the function of the other systems that make up the human body.

To do this, specialists and pharmacists have managed to create anticoagulants such as clexane aimed at avoiding the high risk of bleeding, which may occur during surgery or to reduce coagulation problems in some patients. Here is all the information you need to know about this drug.

What is clexane?

Clexane is a medicine that has enoxaparin sodium as its active substance. It is a compound known as low molecular weight heparins or anticoagulant.

This compound is mainly used before, during or after surgical interventions to prevent or reduce bleeding or the presence of blood clots.

This drug can be purchased as a solution for injection of 20 mg, 40 mg, 60 mg, 80 mg and 100 mg each ampoule. The administration of this medicine can be by subcutaneous route, intramuscularly or by subcutaneous injection.

Note: The doses of this medication depend on the health condition for which it is being given. Usually,1.5 mg per kilo of the patient’s body weight is usually given once a day or 1 mg/kg twice a day (every 12 hours). Your doctor will determine if you need an extra dose.

What is clexane for?

Being an anticoagulant medication, it serves especially as atreatment in surgical patientswho require spinal or epidural anesthesia, require the implementation of extracorporeal circulation equipment or who suffer from the following diseases:

1. Deep vein thrombosis

Venous thromboembolic disease is diagnosed whenblood clots are generated in the deep veinsthat usually occur in the lower extremities. (1)

Therefore, treatment with clexanedecreases the risk of possible clots thatmay lodge in the veins and interrupt blood flow.

To highlight: Venous thrombosis in surgical patients also requires the use of clexane, this as part of the drugs used toprevent complications during the interventionor prophylaxis of the disease.

2. Acute coronary syndromes

Conditions such asunstable angina and myocardial infarction with ST-segment elevation or myocardium without ST elevation, are heart attacks that may require anticoagulants, since these compounds can help the circulatory system to resume its functions. (2)

You should know: Clexane is also frequently used during percutaneous coronary intervention (PCI) , since the drug facilitates the procedures that are performed to correct obstructions in the arteries of the heart.

3. Heart and respiratory failure

Heart failure is one of the diseases that has become common worldwide, especially in elderly people or those who have hereditary histories that indicate conditions related to the cardiac system.

Important: Heart failure generated by thrombosiscan occur, which in turn can lead to: cerebrovascular accident andpulmonary embolismtag. Therefore, studies show that heparin-induced therapy can counteract the effects of heart failure.(3)

Clexane Side Effects

Clexane injection must be administered under a prescription, this is because Miscalculation of the dose of this medication or its excessive use can lead to the following side effects:

• Allergic reaction to the component.
• Renal insufficiency.
•  Risk of bleeding.
• Bruises.
• Headache.
• Skin rashes or hives.
• Decreased red blood cells.
• Increased liver enzymes and blood platelets.

Important: In the presence of any of the above side effects, you should stop using clexane and consult a specialist doctor immediately.

Contraindications of clexane

Anticoagulants such as clexane need to be administered by a specialist who knows the patient’s medical history in advance, especially if he or she suffers from or has presented:

• Ulcer background.
• Take aspirin or aspirin.
• It has mechanical heart valves.
• Patients older than 75 years.
• Pregnant or lactating women.

Key Findings

• Clexane is an anticoagulant medication that contains enoxaparin sodium as the active ingredient.
• Its route of administration is by subcutaneous or intramuscular injections. 
• The main function of this medicine is to prevent the formation of blood clots or counteract those that are already formed.
• It must be administered under strict Medical Supervision , since it could cause internal and/or external bleeding, a decrease in red blood cells and skin bruising.