What is the celestone?
Celestone® is the name of the trademark of a synthetic medication that uses betamethasone as its active ingredient , a chemical compound belonging to the line of corticosteroid anti-inflammatory medications, with an effect on various inflammatory processes in the body . (1)
To highlight: This pharmaceutical product is manufactured in Mexico by the company identified as SCHERING-PLOUGH, SA DE CV . (two)
What is the celestone used for?
- Thanks to the mechanism of action of its active principle, celestone® reduces the release of histamine through the migration of neutrophils to the areas of inflammation, decreasing capillary permeability, edema and the accumulation of mast cells.
- It is used to treat:
- Rheumatic diseases such as rheumatoid arthritis and connective tissue.
- Dermatological, allergic, endocrine and ophthalmic inflammatory processes. (3)
- Respiratory, haematological, gastrointestinal and other inflammatory processes that respond to corticosteroid treatment.
Dosage and routes of administration of celestone
The presentation of celestone® is in the form of a box with vials or a vial, which contains betamethasone sodium phosphate equivalent to 4.0 mg of betamethasone. The administration of this drug is intravenous, intramuscular or intra-articular and the dosage for information may be as follows:
- Celestone® solution for injection: In adults, depending on the severity of the disease, up to a maximum of 8 mg of betamethasone per day may be recommended. For pediatric use, the dose may range from 0.02 to 0.125 mg/kg of body weight per day.
Celestone Side Effects
Results of clinical studies have described that treatment with celestone®, being a steroid drug, can cause some of the following adverse effects in a certain population of patients :
- Possible occurrence of allergic reactions due to patient contact with any chemical component of the formula.
- Hypertension, congestive heart failure.
- Sodium retention , potassium loss , hypokalemic alkalosis and fluid retention .
- Muscle weakness, steroid myopathy, loss of muscle mass, progression of symptoms in myasthenia gravis and osteoporosis.
- Peptic ulcer , pancreatitis, bloating, ulcerative esophagitis , hiccups.
- Impaired wound healing, skin atrophy, fragile and thin skin, petechiae and ecchymosis.
- Possible redness of the area where the injection was given.
- Seizures, increased intracranial pressure, vertigo, and headache .
- Euphoria, major depression , personality changes, hyperirritability, and insomnia .
- Manifestations of latent diabetes mellitus, increased requirements for insulin or oral hypoglycemic agents in diabetic patients.
Important: If the patient observes the appearance of any of the symptoms indicated or another not described, please discontinue its use and notify your doctor .
Contraindications and warnings of celestone
The use of celestone® is contraindicated in the following cases:
- Patient hypersensitivity to any of the components of the formula.
- In patients with systemic mycoses.
- In patients suffering from renal insufficiency.
- During the period of pregnancy and breastfeeding .
- In patients who are under treatment with medicines such as acetylsalicylic acid .
You should know: Provide all information regarding your medical history to your doctor, before starting treatment with this drug.
Avoid if you have:
- History of hypersensitivity to betamethasone or corticosteroid medications.
- History of disorders in the digestive system such as Crohn’s disease.
- History of affective disorders due to the use of corticosteroids.
- History of diabetes, any pathology in the liver or Cushing’s syndrome.
- History of respiratory diseases such as tuberculosis.
Warnings:
- Pharmaceutical products such as celestone®, must be administered with prescription or medical prescription.
- Follow your doctor’s instructions while using this drug.
- Do not exceed recommended dose.
- Administration of this drug into an infected area or into an unstable joint is not recommended.
- Keep this drug stored in a safe, dry and cool place.
- Keep this product out of the reach of children.
University Professional in the area of Human Resources, Postgraduate in Occupational Health and Hygiene of the Work Environment, 14 years of experience in the area of health. Interested in topics of Psychology, Occupational Health, and General Medicine.