Trixone: What is it and what is it for?

What is trixone?

Trixone is the trademark of a chemical compoundclassified as an active ingredient, belonging to the line of drugs with a third-generation and broad-spectrum antibiotic effect calledceftriaxone®, a substance currently manufactured semi-syntheticallywith bactericidal action. (1)

To highlight: This medicine is made in Mexico by the company calledLaboratorios BRULUAGSA, S.A. de C.V. (2)

What is trixone for?

• Trixone®, thanks to its mechanism of action, eliminates bacteria through the inhibition of the synthesis of the bacterial wall, eradicating these pathogenic microorganisms andalleviating the symptoms of infections.
• It is used to treat:
  • Infections in patients with depressed immune systems.
  • Sepsis.
  • Respiratoryinfections, especially pneumonia, as well asthroatand ear infections.
  • Meningitis (infection and inflammation of the membrane lining the nervous system). (3)
  • Abdominalinfections including peritonitis, gallbladder and gastrointestinal tract infections.
  • Infections of the genital tract.
  • Lyme disease.
  • Joint infections,skin infections, as well as infected wounds.
  • Urinary tract infections including kidneys, bladder and urethra.

Dosage and routes of administration of trixone

The presentation of trixone®, is inbox with vials of ampoules with powder of 0.5 g or 1 gand glass or plastic ampoule with 2 or 3.5 ml of diluent respectively for injection. The administration of this medicineis intravenous (IV) or intramuscular (IM) and the dosage for informational purposes may be as follows:

• Infants up to 2 weeks of age:One dose of 20 mg/kg up to a maximum of 50 mg/kg of body weight per day. The duration of treatment will depend on the pathology to be treated.
• Infants and children 3 weeks to 12 months old: 20 to 80 mg/kg per day.
• Children with a body weight of 50 kg or more: 1-2 g of ceftriaxone every 24 hours.
• Adults and children over 12 years of age: 1-2 g of trixona® once a day.

Trixone Side Effects

Clinical data indicate that pharmacological treatment with trixona® may cause some of the following adverse effects in a certain patient population:

• Possible presence of allergic reactions due to contact with any component of the formula.
• May cause bacterial resistance.
• Loose stools or diarrhea , nausea, vomiting , stomatitis and glossitis.
• Leukopenia, granulocytopenia, hemolytic anemia or thrombocytopenia.
• Allergic dermatitis , pruritus, urticaria, edema or erythema multiforme.
• Headaches and dizziness.
• Mycosis of the genital tract and chills.
• Possible vaginal infection .
• Cough and fever .

Important: If during the administration of trixona® (IM or IV) any of these symptoms or another not included in the list appear, please stop its use and consult your doctor .

Contraindications and warnings of trixone

The use of trixona® is contraindicated in the following situations:

• Hypersensitivity to any of the components of the formula or to cephalosporins.
• Preterm newborn infants with bilirubin encephalopathy.
• During the breastfeeding period.

You should know: Provide all the information about your health history to your doctor, before starting treatment with this drug.

Avoid it if you have:

• History of hypersensitivity to ceftriaxone, any cephalosporin, or Penicillin .

Warnings:

• Pharmaceutical products such as trixona® must be administered with a prescription.
• Do not administer trixona® if the solution is not clear, if it contains suspended particles or sediment.
• Do not consume alcoholic beverages during treatment with this drug.
• Inform your doctor if you are being medicated with other drugs for other pathologies, before starting treatment with trixona®.
• There must be a medical recommendation before starting treatment with trixona®, in pregnant women.
• Keep this medicine out of the reach of children.