Upset stomachs are common, some with very acute symptoms that make them easy to treat, although others can make a certain patient uncomfortable in the long run.

In this sense, the pharmaceutical industry has several types of drugs that serve as a treatment for gastric problems at safe levels, made with effective substances such as domperidone.

For this reason, in this article we will discover what domperidone is for, taking into consideration its effects on the body and the recommended doses.

What is domperidone?

Domperidone is an active substance, whichis used in several commercial and generic drugs because itworks as an antiemetic, antinauseant and also controls dopamine.

Domperidone comes as a tablet, oral suspension, or tablet, with oral administration. Doses of domperidone start with 10 mg up to 20 mgevery 6 hours or 8 hours a day.

Note: A medical study mentions the present information: “Domperidone is a dopaminergic antagonist, currently approved for the relief of symptoms of nauseaandvomiting (in both adults and children).” (1)

What is domperidone for?

Domperidone acts asan antagonist to D2 receptors, proteins related to thedopamine neurotransmitterand nervoussystem cognitive functions. In this regard, domperidone is prescribed for:

1. Nausea and vomiting

Domperidone is prescribed for cases of vomiting or nausea, caused by states such as food poisoning , chemotherapy or radiation therapy for cancer and stomach inflammation.

2. Upset stomach

Also called Dyspepsia or evenindigestion , it is a case that occurs mostly due to rapid consumption of food, which eventually causes bloating and abdominal pain.

You should know: The prescribed doses of domperidone for this type of case are 10 mg mg or or 0.3 mg, every or 4 times a dayin the pediatric population, it is recommended to consume the drug before meals.

Domperidone Side Effects

Like many other drugs, domperidone Can bring with it a considerable series of adverse reactions, of which it is worth being warned. Such effects are for example:

  • dry mouth
  • Nervousness.
  • headache.
  • Gastrointestinal spasms.
  • Constipation.

Important: A medical study mentions this information: “Domperidone is a medication that has been questioned that it might increase the risk of side effects on the heart , such as dangerously irregular heartbeats in some patients . ” (two)

Contraindications of domperidone

On the other hand, it is noted that the use of domperidone should be limited in a certain number of patients, to prevent unwanted interactions. For this reason, this drug is contraindicated in cases of:

  • Hypersensitivity to the active substance.
  • Intestinal bleeding.
  • Moderate liver failure.
  • Tumors in the pituitary glands.
  • Patients with renal failure.

You should know: Before starting treatment with domperidone, it is advisable to provide all the information of your health history to the treating doctor , to make the appropriate indications.

Key Findings

  • Domperidone is a substance with antiemetic properties, which is prescribed for stomach upset and nausea.
  • Domperidone comes as a tablet, oral suspension, or tablet , with oral administration.
  • Domperidone can cause side effects such as constipation and dry mouth.
  • Domperidone should not be administered in patients with hypersensitivity , intestinal bleeding or non-benign tumors.

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