Among thegastrointestinal discomfortsare nausea and vomiting, caused by medical treatments against some important pathologies or in the performance of diagnostic tests.

In this sense, the pharmaceutical industry collaborates in the research and development of medicines, whichgreatly reduce the sensations caused by this type of annoying manifestations andamong these drugs is the primperan.

In the following article, we give you all the information about this drug and in what situations you can use it.

What is primperan?

Primperanis an antiemetic drug, i.e. used to prevent or controlemesis, nausea and motion sickness(1). Its active ingredientis metoclopramide hydrochlorideand some excipients such as lactose monohydrate.

The presentation of this medicine is intablets of 10 mgand acts in an area of the brain that prevents nausea and vomiting. The therapeutic indications of this medicine are:

  • Adults: 10 mg, 3 times a day for up to5 days orally.
  • Children and adolescents from 1 to 18 years of age: From 0.1 to 0.15 mg per kilo of body weight, up to a maximumof 0.5 mg 3 times a day, at least every 6 hours to avoid overdose, also orally.

Important: The administration of this medicine is not recommended to patients weighingless than 61 kilograms or in children and adolescents without medical supervision. Likewise, the treatment time should notexceed 3 months, any alteration of the dose should be notified to the specialist doctor.

What is primperan for?

Primperan is a medication used to prevent or treat gastrointestinal disorderssuch as nausea and delayed vomiting, induced by chemotherapy or radiotherapy. (two)

To highlight: This medication is also indicated for the treatment of functional digestive motility disorders, characterized by a set of annoying symptoms such as nausea and vomiting.

Likewise, it is recommended in Post-operative treatments where a recurring problem has been found in patients. (3)

Primperan Side Effects

The use of this medicine Can produce some of the following side effects , generally when high doses are used:

  • Allergic reaction to metoclopramide or any of the components of primperan.
  • You may be at risk of tardive dyskinesia (involuntary movements).
  • Decreased blood pressure.

Note: If you notice any of these adverse reactions, discontinue administration and Consult your doctor .

Primperan contraindications

This medication should not be administered in the following cases:

  • Sensitivity to metoclopramide or any of its components.
  • Children and young adults under 18 years of age, without medical supervision .
  • Patients with a body weight less than 61 kilograms.
  • Patients with neuroleptic malignant syndrome.
  • Children under 1 year.
  • Patients with NADH cytochrome B5 reductase deficiency.
  • women
  • In combination with levodopaDue to mutual antagonism.
  • In combination with alcoholic beverages as they enhance the sedative effect.

Key Findings

  • Primperan is a medication belonging to the group of antiemetic drugs.
  • Primperan is indicated to counteract the effects of nausea and vomiting in cases of chemotherapy and radiotherapy treatments.
  • This drug is also indicated to improve nausea and vomiting after postoperative processes. 
  • The administration of this medicine must be carried out under medical supervision.