What is vengesic?

Vengesic is a drug belonging to the line of commercial products of thepharmaceutical Collins(1), whose formulais composed of the metabolites dexamethasone, phenylbutazone and methocarbamol, which have analgesic® and anti-inflammatory properties.

On the other hand, vengesic® comes in the presentation of tablets or tablets, whose route of administration is oral. The doses in whichthe use of the drug is recommended is between 1 tablet to 3 tablets, 2 to 3 times a day.

Note: A medical study mentions the present information: “Phenylbutazoneis distributed in tissues and body fluidstaking from an important example, synovial fluid.” (2)

What is vengesic for?

Vengesic® exerts amechanism of direct action on the musculoskeletal structure (set of bones, muscle tissues and tendons), also functioning as an anti-inflammatory. But specifically it is usually prescribed in treatment for these diseases:

1. Acute gouty and rheumatoid arthritis

There are two key differences in these types of arthritis. Gout is joint inflammationcaused by an increase in uric acid (a chemical that removes purines), while rheumatoid arthritis occurs due to autoimmune disorders that attack joint tissues.

Of note: The components of this medicine, such as phenylbutazone and dexamethasone, control the production of prostaglandins , which are the main hormones that interact with muscle contractions and the inflammatory response.

2. Osteoarthritis and ankylosing spondylitis

Osteoarthritis is one of the most common cases of joint tissue degradation that exists, and its inflammation or pain mainly affects the protective cartilage in the bones .

In this sense, having lesions as a risk factor, vengesic® and dexamethasone have the ability to decrease the synthesis of prostaglandin hormones when they are released.

You should know: Vengesic® acts in the same way for spondylitis, which is an inflammatory condition that occurs directly in bone structures , mainly in the spine or ribs.

3. Bursitis and tenosynovitis

Vengesic® is prescribed in the same way for bursitis, where the inflammation is located in the area of the synovial bag (found in the knees, elbows or shoulders), which affects the cushioning of these joints and muscles, caused due to injury or trauma.

While tenosynovitis is a complex inflammatory disorder that affects the muscle cord and bone structure (which can affect areas such as the hands or even the feet), caused by inflammation and is also called de Quervain’s disease.

vengesic side effects

Vengesic® can bring with it a series of adverse reactions , which occur in the gastrointestinal system or even in the Central Nervous Systemtag. Among the side effects of vengesic® are the following:

Important: If necessary, you should discontinue the use of this medicine if the reactions affect daily life.

Vengesic contraindications

On the other hand, vengesic® also You certain certain warnings for of its administrationin a certain number of patients, because it could react very negatively. Therefore, its use is not recommended in cases of:

  • Hypersensitivity to active metabolites.
  • Renal insufficiency.
  • Liver failure.
  • Pregnancy.
  • Children not older than 14 years.

To highlight: In order to take advantage of the appropriate functions of these commercial medications, a medical prescription recommended by a health professional must be required.

Key Findings

  • Vengesic® is a commercial product of compounds such as phenylbutazone and dexamethasone, recommended to reduce joint pain and inflammation.
  • Vengesic® is prescribed for rheumatoid arthritis and ankylosing spondylitis.
  • Vengesic® can cause adverse effects such as nervous system depression, drowsiness and fluid retention. 
  • Vengesic® administration is not recommended in pregnant women or in cases of hypersensitivity to the active ingredients.

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