What is mirtazapine?

Mirtazapine is one of the medicines called antidepressants. Its mechanism of action blocks the receptors that inhibit the increase in serotonin and noradrenaline levels, favoring the increase in their levels at the central level, since it is a specific noradrenergic and serotonergic antidepressant.

The active substance of this drug ismirtazapineand also contains lactose monohydrate. This medicine comes as30 mg film-coated tablets.

You should know: The dose of mirtazapine may initially be 15 mg daily in the evening in the first few weeks and according to medical evaluation it may be necessary to increase the doseto 45 mg daily maximum. The administration of this medicine isorally, without chewing and with plenty of waterin a single dose. (1)

It is important to note that this drug ismetabolizedin the liver and is widely distributed in the body by binding easily to plasma proteins, being better tolerable at lower doses. (2)

What is mirtazapine used for?

Treatment with mirtazapine is indicated for states of major depression in adult patients and is a medication widely used in clinical practice (3)tag. It also has uses indepressive states with anxiety symptoms and in sleep disorders. (4)

Note: The effect of mirtazapine is observed in the first two weeks of treatment and it is expected that after 4 weeks of use, the patient will already feel better.

Mirtazapine Side Effects

Taking mirtazapine can cause certain side effects in some patients. The most frequent are the following:

  • Increased appetite and increased body weight.
  • Risk of serotonin syndrome.
  • Orthostatic hypotension.
  • anxiety states.
  • Dry mouth.
  • Signs of infection or sore throat.
  • Drowsiness.

Important: If during drug treatment with mirtazapine you notice the appearance of these or other signs or symptoms, during drug treatment with mirtazapine, talk to your Consult your doctor to suspend or reduce the dose.

Contraindications of mirtazapine

The use of mirtazapine is contraindicated in the following circumstances:

  • In patients with sensitivity to mirtazapine or some of its components.
  • Patients treated with selective serotonin reuptake inhibitors.
  • In the consumption of inhibitory substances of the central nervous system, such as alcoholic beverages.
  • In pregnant or lactating women, since mirtazapine is excreted through breast milk.

Important: It is advisable to review your medical history with your doctor to advise or not the use of this medication.

Key Findings

  • Mirtazapine is a drug that belongs to the group of antidepressants.
  • Mirtazapine is indicated for major depressive states in adults.
  • This medication acts on the central nervous system by stimulating and balancing the production of serotonin and norepinephrine.
  • This medication is a psychotropic and for this reason both its indication and administration must be supervised by a specialist.

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