What is itraconazole?

Itraconazole is a generic medicine andan antifungal active substance, which has a mechanism of action against fungal infections (mycosis), especiallyCandida Spp. Apathogen that can lodgein various parts of the body.

This drug usually comes in the form of a box ofcompressed capsules or 100 mg solutions with an oral route of administration. The doses depend on the case in question, although the initial treatment consists of a maximum of 200 mg of the drug, 2 times a day.

Note: One study adds that: “Itraconazoleis extensively metabolized in the liver giving rise to a large number of metabolites in the body.” (1)

What is itraconazole for?

This medicine is used precisely to reduce the presence of bacteria in the body, in addition to helping to enhance the defenses ofthe immune system. Its clearest functions are as follows:

1. Oral and vulvovaginal candidiasis

Oral candidiasis is both an acute and chronic infection that occurs in the flora of the mouth, while vulvovaginal yeast infection affects women in the uterus and around the vagina, both of which are caused by the same Candida .

To highlight: Itraconazole is recommended to eliminate the cellular functions of this type of fungus in these areas , also serving as a complement together with other drugs for the treatment of these conditions.

2. Lung infections

and mainly affecting the lymph nodes), histoplasmosis, among others.

You should know: The drug itraconazole is recommended, since it is estimated that fungi and bacteria are quite sensitive with respect to the active ingredient of the medication, something effective for its elimination.

3. Skin and nail infections

(skin infections on the skin of the extremities), dermatophytosis (rashes on the nails or epidermis), and pityriasis versicolor (an infection of skin spots caused by different fungi).

Note: This medicine for these cases is also prescribed to children or adolescents , with specific treatment and a medical prescription, with doses that do not exceed 100 mg per day.

Itraconazole Side Effects

Despite its positive actions against agents as harmful as fungi, itraconazole has certain adverse reactions, which in case of presenting them, the drug should be discontinued and a doctor should be seen immediately. Therefore it is recommended that you be aware of:

  • Nausea.
  • Vomiting or loss of appetite.
  • Increased blood pressure.
  • The decrease in minerals such as potassium.

To highlight:One study mentions the following information: “The most common skin rash with These antifungal medications is morbilliform. “(two)

Itraconazole Contraindications

For various safety reasons, itraconazole is contraindicated in a certain number of patients, who need a medical prescriptionif they wish to use this medicine for the mentioned conditions. In this case it is not recommended for:

  • Patients with hypersensitivity to the active metabolite.
  • People with liver or kidney dysfunctions.
  • Patients with heart failure.
  • Pregnant women
  • Keep out of the reach of children under 6 years of age.

Key Findings

  • Itraconazole is a medication made to kill the cell forms of certain fungi and bacteria . 
  • It is recommended for candidiasis, skin and respiratory tract infections. 
  • Itraconazole can cause side effects such as Dizziness or abdominal pain . 
  • It is contraindicated in certain patients and a prescription is required for safe use

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