What is glibenclamide?
Glibenclamide is a generic medicine, but at the same time it is mainly an active ingredient ofantidiabetic character, at the same time that it causes an effect of acute hypoglycemia, ideal for treatingpatients with type 2 diabetes, especially when there are problems with the absorption of other medicines in this class.
The presentation of this drug is in tablets containing 5 mg of the active metabolite, whose route of administration is oral. And although your doses should depend on a prescription, you usually start with2.5 mg per 24 hoursand thus evaluate glucose leveling.
Note: One study adds that: “It is necessary to know that blood and urine glucoselevels should be monitored periodicallywhile being treated with glibenclamide.” (1)
What is glibenclamide for?
Glibenclamide belongs to the sulfonylurea line of medications, whichare used only for cases of type 2 diabetes, promoting the production and secretion of insulin
To highlight: An adequate secretion is made in the organ of the pancreas (a hepatic production of glucose), which is responsible forclosing the complex channels of potassiumand increases those ofcalciumL (which is related to contractions and secretion in the endocrine glands) and thus glibenclamide manages to produce or level blood glucose, similar to mild hypoglycemia.
Glibenclamide Side Effects
Glibenclamide, apart from its complex but positive functions, can bring certain side effects to patients, especially when they are not at the time accustomed to the administration of it. Therefore, you should be aware of:
- Headache and vomiting .
- Increased hunger.
- Tachycardia and increased drowsiness.
- Pain in the abdomen.
- Irritability.
Glibenclamide Contraindications
There are also certain warnings about the administration of glibenclamide, may have negative reactions in a certain number of patients or people, with different disorders or special medical conditions. Therefore, this drug is not recommended in the following cases:
- People with type 1 diabetes.
- Diabetic coma (complication and loss of consciousness caused by diabetes).
- Renal insufficiency.
- Women in the stage of pregnancy.
- Patients with hypersensitivity to the active metabolite.
Important : It is necessary to go to a medical specialist, to monitor your diabetic condition and opt for a prescription, if the use of this drug and its doses is really required.
Key Findings
- Glibenclamide is a sulfonylurea active substance used in the treatment of type 2 diabetes mellitus.
- It can help with insulin secretion by blocking calcium ion channels.
- Glibenclamide may increase appetite or cause drowsiness as side effects.
- The use of glibenclamide is not indicated for pregnant women .
University Professional in the area of Human Resources, Postgraduate in Occupational Health and Hygiene of the Work Environment, 14 years of experience in the area of health. Interested in topics of Psychology, Occupational Health, and General Medicine.