What is vessel due f?

Vessel due f® is a pharmaceutical medicinethat contains as its active ingredient sulodexide(1), a chemical compound belonging to the line of anticoagulant medicines, with an effect on blood vesselsaffected by venous insufficiency processes.

To highlight: This medicine is manufactured in Italy by the company calledCatalent Italy S.p.A. (2)

What is vessel due f for?

  • The vessel due f® thanks to sulodexide, has antithrombotic and profibrinolytic properties (reduces the formation of blood clots) as well as anti-inflammatory effects, since it reduces the deposit of C-reactive protein and MAC (membrane attack complex), contributing to blood circulation problemslinked to venous insufficiency for various reasons, restoring the thickness of the glycocalyx of the vascular endothelium. (3)
  • It is used to treat:
    • Chronic venous disease, including venous leg ulcers and post-thrombotic syndrome. (4)
    • Prophylaxis of recurrent venous thrombosis.
    • Nephropathy secondary todiabetesmellitus.

Dosage and routes of administration of vessel due f

The presentation of the vessel due f®, is inboxes with 25 or 50 capsules containing 25 mg of sulodexideeach and in solution for injection in ampoules of 2 ml 600 LRU. The administration is according to the presentation, beingoral and intramuscular or intravenous respectively andthe dosage for information purposes may be as follows:

  • Capsules: One or two capsules twice daily between meals (500 to 1000 LRU daily) for three months or more.
  • Solution for injection: One ampoule once a day for 15 to 20 continuous days.

Side effects of vessel due f

Therapeutic treatment with vessel due f® may cause some of the following side effects in a certain patient population:

  • Possible allergic reactions due to contact with any component of the formula.
  • Epigastric pain, nausea andvomiting.
  • Skin rash, redness or small bruising at the injection site.
  • Altered laboratory test results.
  • Hyperglycemia indiabetic nephropathy.
  • Insomnia.
  • Cerebral hemorrhage.
  • Otitis externa with otorrhoea.

Important: If any of these symptoms or other symptoms do not appear during treatment with vessel due f®, pleasediscontinue use and notify your doctor.

Contraindications and warnings of vessel due f

The use of vessel due f®is contraindicatedin the following situations:.

  • Known hypersensitivity to sulodexide, heparin, and other glycosaminoglycans.
  • Patients suffering from diathesis or hemorrhagic disease.
  • During the period of pregnancy andbreastfeeding.

You should know: Before starting treatment with this medicine, give all the information about your health history to yourdoctor.

Avoid it if you have:

  • History of hypersensitivity to sulodexide, heparin, and other glycosaminoglycans.


  • Pharmaceutical products such as vessel due f® must be administered with a prescription or prescription.
  • Concomitant administration of vessel due f® with other anticoagulant medicinal products may increase its effect.
  • Caution should be maintained in case of overdose, as bleeding may occur.
  • Keep this medication out of reach of children.

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