What is venlafaxine?

Venlafaxineis a chemical compound classified as active ingredient, which belongs to the line of medicines inhibitors of serotonin and norepinephrine reuptake (SNRIs), with antidepressant effect in adults(1)

What is venlafaxine for?

  • Venlafaxine, thanks to its mechanism of action, enhances the activity ofneurotransmittersin thecentral nervous system (CNS). This action allows to increase the amount of the neurotransmitters serotonin andnoradrenaline, substances that help thebrainmaintain mental balance.
  • It is used to treat:
    • Depressionand/or depression withanxiety(2)
    • Generalized anxiety disorders.
    • Long-term social anxiety or phobia.
    • Panic disorder.
    • Neuropathic pain. (3)

Dosage and routes of administration of venlafaxine

Venlafaxine is dispensed as 37.5 mg, 50 mg, 75 mg, and 150 mgextended-release capsules. The route of administrationis oraland the dosage as a referential may be as follows:

  • Social anxiety disorder: The recommended dose to start treatment is 75 mg/day, administered in a single dose for four to seven days and then if required, an adjustment is made.
  • Depression: It is recommended to start with a dose of 75 mg and then adjust.

What products contain venlafaxine?

Some of the medicines that contain venlafaxine are:

  • Benolaxe®
  • Dislaven retard®
  • Mazda®
  • Vextor®

Benolaxe®

  • Benolaxe® is an antidepressant medicine that uses venlafaxine as its active ingredient.
  • It is indicated in Pharmacological therapy for major depression or the prevention of recurrence of major depressive episodes.

Dislaven retard®

  • Dislaven retard® is an antidepressant that belongs to the serotonin and norepinephrine reuptake inhibitors , which contains venlafaxine.
  • It is used in the treatment of depression and anxiety disorders.

Mazda®

  • Mazda® is a medicine that contains venlafaxine as an active ingredient and is sold in capsules of different concentrations.
  • It is indicated in the treatment of generalized anxiety disorder, social anxiety disorder and panic disorder.

Vextor®

  • Vextor® is a drug used against some disorders in the central nervous system, which uses venlafaxine as an active ingredient.
  • It is used to treat depression and anxiety in adults.

Venlafaxine Side Effects

The therapeutic treatment with venlafaxine Can cause some of the following adverse effects in certain patients:

  • Possible appearance of allergic reactions due to contact with any component of the formula.
  • Asthenia, fatigue, yawning, dry mouth.
  • Abnormal dreams, decreased libido, vertigo, increased muscle tone.
  • Apathy, hallucinations, myoclonus, agitation, impaired coordination, and swaying.
  • Seizures, manic reaction, neuroleptic malignant syndrome, serotonin syndrome.
  • Increased blood pressure in some people.

Important: If any of these symptoms appear or any other not included in this list, please stop using it and consult your doctor .

Contraindications and warnings of venlafaxine

The use of venlafaxine is contraindicated in the following cases:

  • Hypersensitivity to any of the formula’s components.
  • In patients taking monoamine oxidase inhibitors (MAOIs).
  • During the pregnancy period.
  • During the Breastfeeding
  • In patients under 18 years of age.

To be highlighted: Provide all the information about your health history, before starting treatment with venlafaxine.

Avoid it if you have:

  • History of hypersensitivity to venlafaxine.
  • Recent history of myocardial infarction.

Warnings:

  • This pharmaceutical product must be administered with caution or by prescription.
  • Venlafaxine should not be started for at least 14 days after discontinuation.
  • Venlafaxine should not be administered for at least 7 days before starting treatment with any MAOI.
  • Products like venlafaxine should be kept away from children.
  • This drug can cause drowsiness and affect alertness, so caution should be exercised if you are going to drive or operate precision machinery.

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