What is tramacetam?

Tramacet® is the registered trademark of a pharmaceutically manufactured synthetic medicine, which uses tramadol and paracetamol as active ingredients , two chemical compounds belonging to the line of analgesic medicines, with an effect on certain acute or chronic ailments in the body .

To highlight: This pharmaceutical product is made by the company named JANSSEN-CILAG, SA de CV . (1)

What is Tramacet used for?

  • Thanks to the joint mechanism of action (tramadol/paracetamol), tramacet® acts by binding an M1 metabolite to µ-opioid receptors and weakly inhibiting the reuptake of norepinephrine and serotonin. This action allows to enhance the analgesic effect of both substances with a lower individual concentration, for the benefit of patients with pain from various pathologies.
  • It is used to treat:
    • Moderate to severe, acute and chronic pain. (two)

Dosage and routes of administration of tramacet

The presentation of tramacet® is in the form of tablets , which contain 37.5 mg tramadol hydrochloride and 325 mg paracetamol. The administration is orally and the informative dosage can be as follows:

  • Children over 16 years of age and adults: 1 or 2 tablets every 4 to 6 hours, depending on the patient’s response to pain relief.

Side Effects of Tramacet

Treatment with tramacet® can cause some of the following adverse effects in a certain patient population:

  • Possible allergic reactions due to patient contact with any of the components of the formula.
  • Itching, skin rash, increased sweating.
  • Asthenia, fatigue, hot flashes.
  • Abdominal pain, constipation , diarrhea , dyspepsia, flatulence, xerostomia, vomiting .
  • Nausea, vertigo, tinnitus and drowsiness.
  • Anorexia, anxiety , confusion, euphoria, insomnia , nervousness.
  • Hypertension or hypotension, urinary retention .
  • Ataxia, seizures, hypertonia, migraine , involuntary muscle contractions, paresthesia, vertigo.
  • Amnesia, depression , drug abuse, hallucinations , impotence, nightmares, abnormal thoughts.
  • withdrawal syndrome .

Important: If during treatment with tramacet® the patient shows any of these symptoms or another that is not on the list, please stop using it and consult your doctor .

Tramacet contraindications and warnings

Treatment with tramacet® is contraindicated in the following circumstances:

  • Patient hypersensitivity to any of the components of the formula.
  • Patients suffering from acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic drugs.
  • People who are being medicated with MAO inhibitors.
  • In children under 15 years of age.
  • During the pregnancy period.
  • During breastfeeding .

You should know: Before starting treatment with this drug, the patient must provide his doctor with all the information about his health history .

Avoid if you have:

  • History of hypersensitivity to any of the components of this medicine.
  • History of medication with MAO inhibitors.

Warnings:

  • Pharmaceutical products such as tramacet®, must be administered with a prescription or medical prescription.
  • You should bear in mind that treatment with this medicine must be supervised by a specialist doctor, so avoid self-medication.
  • Follow your doctor’s instructions to avoid possible poisoning episodes.
  • Do not alter the dose recommended by your doctor.
  • Keep this product out of the reach of children.

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