What is strong metrigen?

Strong Metrigen® is the registered trademark of a synthetic medicine, which uses the combination of hormones such as progesterone (1) and estradiol benzoate (2) , chemical compounds belonging to the line of estroprogestative medicines, with an effect on certain pathologies in the women ‘s menstrual cycle

To highlight: This pharmaceutical product is produced by the company named Aspen México S. de RL de CV (3)

What is strong metrigen used for?

  • Thanks to the mechanism of action of its active ingredients, metrigen fuerte® stimulates the production of sex hormones to restore normal menstruation in women.  
  • It is used to treat: 
    • Selected cases of primary and secondary amenorrhea. (4)
    • Oligo and hypomenorrhea.
    • Dysfunctional bleeding without overt organic disorders.

Dose and routes of administration of strong metrigen

The presentation of metrigen fuerte® is in a cardboard box with 1 syringe of 1 ml, containing 50 mg progesterone and 5 mg estradiol benzoate. The route of administration of this medication is intramuscular and the dosage as a reference may be as follows: 

  • Strong Metrigen® injectable solution: Generally the dose to be administered is one injection of 1 ml per day. 

Strong Metrigen Side Effects

Therapeutic treatment with strong metrigen® can cause in a certain population of patients , some of the following adverse reactions: 

  • Possible allergic reactions due to patient contact with any of the components of the formula.
  • Post medication amenorrhea.
  • Changes in cervical secretion.
  • Increase in size of uterine fibroids.
  • Aggravation of endometriosis.
  • Appearance of certain vaginal infections, for example candidiasis.
  • Nausea, vomiting , cholelithiasis, cholestatic jaundice .
  • Risk of endometrial hyperplasia and carcinoma when estrogens are administered.
  • Erythema nodosum and rash.
  • Discomfort in the cornea.
  • Headache, migraine , mood swings.
  • Fluid retention , premature epiphyseal closure, and changes in body weight.

Important: If during treatment with this drug the patient presents some of these symptoms or another not described in the list, please stop using it and consult your doctor .

Strong Metrigen Contraindications and Warnings

The use of metrigen fuerte® is contraindicated in any of the following circumstances: 

  • Patient hypersensitivity to any of the components of the formula.
  • Patients with thrombophlebitis and thromboembolic processes.
  • Severe liver failure.
  • Patients with cholestatic jaundice.
  • Patients with rotor syndrome and Dubin-Johnson syndrome.
  • In undiagnosed vaginal bleeding.
  • During the period of pregnancy or while breastfeeding .

You should know: Provide your doctor with all the information about your health history, before starting treatment with this drug.

Avoid if you have:

  • History of hypersensitivity to the components of the drug.
  • History of cardiovascular disorders such as thrombophlebitis or thromboembolic processes.
  • History of liver disease.
  • History of pregnancy jaundice.

Warnings:

  • Pharmaceutical products such as strong metrigen®, must be administered with prescription or medical prescription.
  • Follow your doctor’s instructions while using this medication.
  • Do not exceed recommended dose.
  • Strong Metrigen® induces a withdrawal bleed, which usually occurs 3 to 5 days after the treatment period.
  • Do not use this medicine to treat threatened abortion.
  • Administer with great caution in patients with varicose veins , as well as patients with renal failure.
  • Keep this product out of the reach of children.

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