What is serratiopeptidase?

Serratiopeptidase is a medicine of biological origin, which comes from the proteolytic enzyme isolated and synthesized from bacteria present in the intestinal wall of the silkworm, which has properties as an anti-inflammatory and fibrinolytic agent with an effect on various conditions in the body.

What is serratiopeptidase used for?

  • Thanks to its great therapeutic properties, serratiopeptidase safely interrupts inflammation , in addition to dissolving necrotic tissue regardless of its location.
  • It is used to treat:
    • Inflammation and mucopurulent discharge from otorhinolaryngology infections.
    • Inflammation and seropurulent exudate in pulmonology.
    • Swelling, inflammatory exudate and edema.
    • Hematoma resorption in surgery, traumatology and orthopedics.
    • Inflammatory processes in gynecological surgery.

Dosage and routes of administration of serratiopeptidase

The presentation of serratiopeptidase is usually in capsules, containing 5 or 10 mg serratiopeptidase. The administration of this medication is orally and the dosage as a reference can be as follows:

  • Children from 5 to 12 years of age: 1 capsule of 5 mg, 3 times a day.
  • Children over 12 years of age and adults: 2 capsules of 5 mg, 3 times a day or 1 capsule of 10 mg, every 8 hours.

What products contain serratiopeptidase?

Some of the medicines that contain serratiopeptidase are:

  • Damizen®
  • Danzen®


  • Damizen® is the trademark of a drug that uses serratiopeptidase as the active substance.
  • It is used to treat various inflammatory processes in the body.


  • Danzen® is a medicine that uses the isolated proteolytic enzyme present in the intestinal wall of the silkworm called serratiopeptidase.
  • It is used to mitigate the symptoms of different inflammatory processes in the body.
  • For more information about this medicine, see Danzen: What is it and what is it for? .

Serratiopeptidase Side Effects

Data from clinical studies indicate that treatment with serratiopeptidase may cause some of the following adverse effects in a certain patient population:

  • Possible allergic reactions due to patient contact with any component of the formula.
  • Anorexia and nausea.
  • Acne.
  • Stevens-Johnson syndrome and toxic epidermal necrolysis.
  • Liver dysfunction or jaundice .

Important: If during treatment with serratiopeptidase the patient manifests some of these symptoms or another not described, please discontinue use and consult your doctor .

Contraindications and Warnings of Serratiopeptidase

The use of serratiopeptidase is contraindicated in the following circumstances:

  • Hypersensitivity of the patient to any of the components of the drug.
  • Patients with blood dyscrasias.
  • People with hypoprothrombinemia.
  • In cases of yellow degradation of the liver and acute pancreatitis.
  • During the period of pregnancy or breastfeeding without medical approval.

You should know: The patient must provide all the information about his health history to his doctor, before starting treatment with this medication.

Avoid if you have:

  • History of hypersensitivity to the components of the drug.
  • Alterations in blood coagulation.
  • Renal and/or hepatic alterations.


  • Pharmaceutical products such as serratiopeptidase, must be administered with prescription or prescription.
  • Follow your doctor’s instructions during treatment with this medicine.
  • Do not exceed the dose prescribed by your doctor.
  • Keep this product out of the reach of children.

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