What is rivaroxaban?

Rivaroxaban is the name of a chemical compound classified as an active principle by medical science, which works as an anticoagulant and antithrombotic medication to correct diseases and conditions in the circulatory system in some patients. (1)

What is rivaroxaban used for?

  • Rivaroxaban works by blocking a blood clotting factor (factor xa) and therefore helps by reducing the tendency of the blood to form clots in different parts of the body, but essentially in the brain , lungs and legs, in addition to preventing their reappearance. 
  • It is used to treat: 
    • Deep vein thrombosis (DVT).
    • Pulmonary Embolism (PE).
    • Prevention of venous thromboembolism.
    • Prevention of venous thrombosis after hip or knee replacement surgery. (two)
    • Prevention of systemic embolism in adults with nonvalvular atrial fibrillation. (3)
    • Patients with blood clot.
    • Prevention of atherothrombotic events in adult patients with coronary artery disease.
    • Prevention of stroke.

Dosage and routes of administration of rivaroxaban

The presentation of rivaroxaban depends on the manufacturing laboratory, however it is usually sold in 10 mg, 15 mg and 20 mg tablets . The administration of this drug is orally, being easily absorbed with food and the dose for information may be as follows:

  • Prevention of stroke and systemic embolism: The recommended dose is 20 mg once a day and the duration of treatment will be indicated by your treating physician.
  • Treatment of DVT, treatment of PE, and prevention of recurrences of DVT and PE: The recommended dose for initial treatment of acute DVT or PE is 15 mg twice daily for the indicated duration. by your doctor, followed by 20 mg once daily, for the prevention of recurrences of DVT and PE.

What products contain rivaroxaban?

Some of the medicines that contain rivaroxaban or another active substance with the same anticoagulant effect are:

  • Apixaban Tad®
  • Eliquis®
  • Xarelto®

Apixaban Tad®

  • Apixaban tad® is a synthetic drug that contains apixaban as an active ingredient with an anticoagulant effect in concentrations of 2.5 mg and 5 mg.
  • This medicine is used to prevent the risk of venous thromboembolism, stroke and systemic embolism in adult patients.


  • Eliquis® has as its active principle apixaban , a chemical compound with anticoagulant properties in concentrations of 2.5 mg and 5 mg.
  • This drug is used for the prevention of stroke and systemic embolism in adults with nonvalvular atrial fibrillation.


  • Xarelto® is a synthetic drug whose active ingredient is rivaroxaban , an anticoagulant medication in different concentrations.
  • It is used to treat venous thromboembolism (VTE) and its recurrences in term newborns, infants, children and adolescents under 18 years of age.
  • For more information about this medicine, see What is xarelto and what is it used for? 

Side effects of rivaroxaban

The consumption of rivaroxaban can cause in certain patients some of the following adverse reactions :

  • Possible allergic reactions due to contact with any component of the formula.
  • Stevens-Johnson syndrome.
  • Toxic epidermal necrolysis.
  • DRESS syndrome.
  • Syncope and dizziness.
  • hemorrhages.
  • bruising.
  • Anemia .
  • Thrombocytosis.
  • Allergic dermatitis , angioedema and allergic edema.

Important: If any of these symptoms or any other symptoms not included in the list appear during treatment with rivaroxaban, stop using it and notify your doctor.

Contraindications and warnings of rivaroxaban

Rivaroxaban is contraindicated in the following circumstances:

  • Hypersensitivity to any of the formula’s components.
  • Patients with liver disease associated with coagulopathy.
  • Patients with active, clinically significant bleeding such as gastrointestinal ulceration and malignancy.
  • Concomitant treatment with any other anticoagulant.
  • During pregnancy or lactation .

To highlight: Provide your doctor with all the information about your medical history, before starting treatment with rivaroxaban.

Avoid if you have:

  • Hepatic or renal failure.
  • Medication with other drugs for other pathologies, without consulting the doctor.
  • Recent surgical intervention.
  • Very high, uncontrolled blood pressure.
  • Heart valve prosthesis.


  • During treatment with rivaroxaban there must be constant medical surveillance.
  • This medication must be administered under a prescription.
  • Do not administer this drug in children with a body weight less than 30 kg.
  • Keep this medicine out of the reach of children.
  • Do not take rivaroxaban together with other drugs without your doctor’s approval.
  • Follow the medical instructions regarding the use of this medicine.

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