What is pirifur?
Pirifur® is the trademark of a combined synthetic drug , which uses nalidixic acid (1) and phenazopyridine as active ingredients , two chemical compounds that belong to the line of antibiotic and antiseptic-analgesic drugs with an effect mainly on the urinary tract. .
To highlight: This pharmaceutical product is made by the company named SANOFI AVENTIS WINTHROP, SA DE CV (2)
What is pirifur used for?
- Thanks to the mechanism of action of its active ingredients, pirifur® acts as a bacteriostatic (3) , since it inhibits bacterial growth and reproduction , in addition to relieving pain, burning, irritation and discomfort in the urinary tract caused by urinary tract infections. bacteria such as E. coli, Enterobacter sp., Klebsiella sp., among others.
- It is used to treat:
- Uncomplicated urinary tract infections and associated symptoms caused by susceptible gram -negative bacteria.
- Inflammation of the bladder and urinary tract.
Dosage and routes of administration of pirifur
Pirifur® is sold in tablets with 500 mg of nalidixic acid and 50 mg of phenazopyridine . The route of administration is oral and the dosage as a reference may be as follows:
- Tablets: The suggested dose is 2 tablets 2 to 4 times a day, according to the medical diagnosis.
Side effects of pirifur
Clinical data indicate that treatment with pirifur® may cause some of the following adverse effects in a certain patient population:
- Possible allergic reactions due to contact with any component of the formula.
- In neonatal and pediatric patients, increased intracranial pressure with bulging of the anterior fontanel, papilledema, and headache.
- Dyspepsia, abdominal pain , nausea, vomiting and diarrhea .
- Cutaneous rash, pruritus, hives, angioedema, joint stiffness.
- Drowsiness, weakness, paresthesias and vertigo.
- Toxic psychoses or mild seizures.
- Epilepsy or cerebral arteriosclerosis in the case of overdose.
- Palsy of the sixth cranial nerve has been observed in rare cases.
Important: If you observe the appearance of any of these symptoms during the administration of pirifur®, please discontinue its use and notify your doctor .
Contraindications and warnings of pirifur
The use of pirifur® is contraindicated in the following cases:
- Known hypersensitivity to nalidixic acid or phenazopyridine.
- Patients with liver and kidney failure.
- Persons under 18 years of age.
- Patients in case of glucose 6-phosphate dehydrogenase deficiency.
- In the period of pregnancy.
- During breastfeeding .
You should know: Before starting treatment with this drug, provide all information about your health history to your doctor.
Avoid if you have:
- History of hypersensitivity to nalidixic acid or phenazopyridine.
- History of seizures.
Warnings:
- Pharmacological products such as pirifur® must be administered with a prescription or prescription.
- The patient should avoid exposure to intense sunlight during the administration of this drug, so as not to suffer from photosensitivity reactions.
- Avoid overdosing of this medication, so as not to exacerbate adverse effects.
- This product should be kept out of the reach of children.
- Follow your doctor’s instructions during the treatment period.
University Professional in the area of Human Resources, Postgraduate in Occupational Health and Hygiene of the Work Environment, 14 years of experience in the area of health. Interested in topics of Psychology, Occupational Health, and General Medicine.