What is oroxadin?

Oroxadin® is the registered trademark of a pharmaceutical -manufactured medication that contains ciprofibrate (1) as its main active ingredient , a chemical compound belonging to the line of medications with lipid-lowering properties, with an effect on blood lipid levels .

To highlight: This medication is produced by the company named SANOFI-AVENTIS DE MÉXICO, SA de CV (2)

What is oroxadin used for?

  • Thanks to the mechanism of action of its active principle, oroxadin® acts to inhibit the hepatic biosynthesis of cholesterol , inducing the reduction of plasma cholesterol and triglycerides , an action that is attributed to the reduction of low-density atherogenic fractions. This balances blood lipid levels in patients with dyslipidemia problems. 
  • It is used to treat: 
    • Severe isolated hypertriglyceridemia.
    • Mixed hyperlipidemia such as the combination of low HDL cholesterol, elevated triglycerides, and elevated apolipoprotein A levels, hypercholesterolemia, and other combined forms. (3)

Dosage and routes of administration of oroxadin

The presentation of oroxadin® is in the form of a box with 30 capsules, which contain 100 mg ciprofibrate. This medication is administered orally and its referential dosage may be as follows:

  • Adults: The indicated dose is usually 1 capsule of 100 mg daily, as directed by your doctor.

Oroxadin Side Effects

Results of clinical studies have described that treatment with oroxadin® has caused some of the following adverse effects in a certain group of patients :

  • Possible allergic reactions due to patient contact with any of the components of the formula.
  • Urticaria, pruritus, photosensitivity reaction and eczema.
  • Headache , dizziness, drowsiness and vertigo.
  • Pneumonitis and pulmonary fibrosis.
  • Nausea, vomiting , diarrhea , dyspepsia, and abdominal pain .
  • Fatigue, myalgia, alopecia, erectile dysfunction.
  • Myositis, myopathy and rhabdomyolysis.

Important: If any of these symptoms appear during treatment with this drug, please discontinue use and consult your doctor.

Oroxadin contraindications and warnings

The use of oroxadin® is contraindicated in any of the following cases mentioned below:

  • Hypersensitivity of the patient to any of the components of the drug.
  • Patients suffering from glucose or lactose malabsorption syndrome .
  • People with severe kidney failure.
  • In the case of patients with galactosemia, cholestasis, cytolysis and cholelithiasis.
  • Impaired liver function.
  • During the pregnancy period.
  • Patients with lactase deficiency.
  • During breastfeeding .
  • In any hypoalbuminemia situation, such as nephrotic syndrome.

You should know: Provide your doctor with all available information regarding your health history , before starting treatment with this medication.

Avoid if you have:

  • History of hypersensitivity to ciprofibrate or any other medication in the fibrate group.

Warnings:

  • Pharmaceutical products such as oroxadin® must be administered with prescription or medical prescription.
  • Follow your doctor’s instructions while using this drug.
  • Do not exceed the dose recommended by your doctor.
  • Do not take this drug in combination with other fibrate drugs.
  • Keep this product out of the reach of children.

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