What is nexium?

Nexium® is the trade name of a synthetic medicine that uses esomeprazole as the active principle, a chemical substance belonging to the line of medicines called proton pump inhibitors, with an effect on pathologies in the stomach .

To highlight: This pharmaceutical product is produced by the company ASTRAZENECA SA de CV (1)

What is the nexium used for?

  • Thanks to the intervention of its active principle, nexium® acts in the gastrointestinal tract , reducing the amount of acid produced by the stomach. This action relieves stomach discomfort in many patients, caused by uncontrolled acid production. 
  • It is used to treat: 
    • Erosive reflux esophagitis .
    • Long-term esophagitis healed (relapses).
    • The symptoms of gastroesophageal reflux disease (GERD).
    • Upper gastrointestinal symptoms associated with NSAID therapy.
    • Patients with Zollinger Ellison syndrome .
    • Patients at risk of gastric ulcers.
    • Duodenal ulcer healing associated with helicobacter pylori infection, in a preventive way.
    • Relapses in patients with peptic ulcers due to helicobacter pylori, in a preventive way.
    • Prevention of esophageal cancer and stomach ulcers.

Dosage and routes of administration of nexium

The presentation of nexium® is in boxes with 7, 14 and 28 sachets, containing esomeprazole magnesium trihydrate equivalent to 2.5, 5, 10, 20 and 40 mg of esomeprazole. The administration of this medication is orally and the dosage for information may be as follows:

  • Treatment of erosive reflux esophagitis: A dose of 40 mg daily is recommended for four to eight weeks.
  • Prevent relapses in long-term treatment of healed esophagitis: The dose may be 20 mg daily.
  • Symptomatic treatment of GERD: A dose of 20 mg daily in patients without esophagitis.
  • Treatment of upper gastrointestinal symptoms associated with NSAID therapy: A dose of 20 mg daily in patients suffering from upper gastrointestinal symptoms due to NSAID therapy.

nexium side effects

Data from clinical studies describe that treatment with nexium® can cause, in a certain group of patients , some of the following adverse effects:

Important: If during treatment with nexium® some of these symptoms or another not described appear, please discontinue use and consult your doctor .

Contraindications and warnings of nexium

The use of nexium® is contraindicated in any of the following cases:

  • Patient hypersensitivity to any of the components of the drug formula or to drugs from the group of proton pump inhibitors.
  • During the pregnancy period.
  • During breastfeeding .

You should know: Before starting a treatment with proton pump inhibitor drugs such as nexium®, provide all the information regarding your health history to your doctor.

Avoid if you have:

  • History of hypersensitivity to esomeprazole or drugs from the group of proton pump inhibitors.
  • If you are taking a medicine containing nelfinavir


  • Pharmaceutical products such as nexium®, must be administered with prescription or medical prescription.
  • Follow your doctor’s instructions while using nexium®.
  • Do not exceed the dose indicated by your doctor.
  • Medical surveillance should be maintained in those long-term treatments with this drug.
  • Tell your doctor if you are receiving medication to treat other pathologies.
  • Keep this product out of the reach of children.

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