What is moxifloxacin?

Moxifloxacin is a synthetic drug with broad-spectrum antibiotic effect, belonging to the group of fluoroquinolones, which is used to treat certain infections or diseases caused by bacteria or microorganisms in skin, tissue and other organs. (1)

What is moxifloxacin used for?

  • The mechanism of action of moxifloxacin inhibits the enzymes necessary for the replication, transcription, recombination and repair of DNA in bacteria, preventing their reproduction and development .
  • It is used to treat:
    • Acquired pneumonia. (two)
    • Acute exacerbation of chronic bronchitis .
    • Tuberculosis. (3)
    • Acute bacterial sinusitis.
    • Skin and soft tissue infections .
    • Intra-abdominal infections.

Dosage and routes of administration of moxifloxacin

The presentation of moxifloxacin is in tablets, with moxifloxacin hydrochloride equivalent to 400 mg of moxifloxacin and is also sold in the form of eye drops . The administration is orally and its most usual dose is as follows:

  • Tablets: 1 tablet of 400 mg every 24 hours and its therapeutic duration will be under medical recommendation.
  • Eye drops : Adults up to advanced age and children, 1 drop in the affected eye or eyes 3 times a day (morning, afternoon and evening).

What products contain moxifloxacin?

Some of the medicines that contain moxifloxacin are:

  • Abimox®
  • Actira®
  • Abiox®
  • Vigamox®

Abimox®

  • Abimox® is a medicine whose active ingredient is moxifloxacin and its presentation is in the form of eye drops.
  • It is used to treat infections of the eyeball ( conjunctivitis ), caused by bacteria.

Actira®

  • Actira® is a synthetic medicine that belongs to the group of antibiotics called fluoroquinolones and whose active ingredient is moxifloxacin.
  • This drug is used to eliminate bacteria that cause infections in the airways, skin and soft tissues.

Abiox®

  • Abiox® is a synthetic drug that contains moxifloxacin as an active ingredient, which belongs to the group of antibiotics called fluoroquinolones.
  • This drug is indicated in the treatment of bacterial infections when they are caused by bacteria sensitive to this active ingredient.

Vigamox®

  • Vigamox® has moxifloxacin as its active ingredient , a chemical compound that belongs to the group of antibiotics.
  • This medicine is an ophthalmic anti-infective, indicated for the treatment of conjunctivitis since its presentation is in eye drops.

side effects of moxifloxacin

The use of moxifloxacin may cause some of the following adverse reactions in certain patients :

  • Possible allergic reactions due to contact with any component of the formula.
  • Cardiac arrhythmia, palpitations, QT interval prolongation, tachyarrhythmia, among others.
  • Phototoxicity, skin rash, Stevens-Johnson syndrome, and toxic epidermal necrolysis.
  • Abdominal pain, indigestion, diarrhea , altered sense of taste, vomiting and nausea.
  • Agranulocytosis, aplastic anemia and hemolytic anemia.
  • Hepatic necrosis, hepatitis, jaundice , hepatic failure.
  • Risk of hemolysis in patients with glucose-6-phosphate dehydrogenase deficiency.

Important: If any of the above adverse effects or any other not included in the list appear, stop administration and consult your doctor.

Contraindications and warnings of moxifloxacin

Treatment with moxifloxacin is contraindicated in the following cases:

  • Hypersensitivity to the components of the formula.
  • Hypersensitivity to antibiotics of the quinolone family.
  • During pregnancy or lactation .

To be noted: It is recommended that before starting treatment with moxifloxacin, you provide all information about your medical history to your doctor.

Avoid if you have:

  • Medication with drugs for other pathologies without prior medical consultation.
  • History of tendon disorders.

Warnings:

  • This medication in tablet form should not be given to adolescents under 18 years of age.
  • This pharmaceutical product must be administered with a prescription or medical prescription.
  • During treatment with moxifloxacin prolonged exposure to sunlight should be avoided.
  • During the consumption of this drug, tendinitis or tendon rupture may occur in people over 60 years of age.
  • There may be a risk of myasthenia gravis.
  • There is a risk of alterations in the central nervous system .
  • This drug should only be used in the absence of other therapeutic options.
  • Keep this medicine out of the reach of children.
  • Do not take after the expiration date.

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