What is macrofurin?
Macrofurin® is a synthetic medication that contains nitrofurantoin as an active ingredient , a chemical compound that is part of the line of broad-spectrum antibiotics, which is used to treat infections caused by germs and bacteria that cause discomfort at the tract level. urinary in men and women. (1)
To highlight: Macrofurin® is a drug patented by the laboratory named MAVI FARMACÉUTICA, SA DE C,V. (two)
What is macrofurin used for?
- Macrofurin® has great bactericidal power in urine , that is, its active ingredient alters ribosomal proteins and other macromolecules in bacteria, resulting in aerobic metabolism, DNA and RNA synthesis, and bacterial wall synthesis. inhibited, killing bacteria .
- It is used to treat:
- Asymptomatic bacteriuria lodged in the urinary tract.
- Recurrent, uncomplicated urinary tract infections caused by susceptible bacteria. (3)
- Antibiotic prophylaxis for the presence of anatomical and/or functional abnormalities of the urinary system. (4)
- Prophylaxis for surgical procedures, pelvic prolapse and urinary incontinence.
- Urinary tract infection not complicated by the use of a bladder catheter. (5)
Dose and routes of administration of macrofurin
The presentation of macrofurin® is in capsules with 100 mg of nitrofurantoin, in a box of 40 capsules. The administration is orally and the dose for information may be as follows:
- Adults: 50 to 100 mg every 6 hours for uncomplicated urinary tract infections.
- Children over 12 years of age or weighing over 40 kg: 1 50 mg capsule, every 4 times a day.
- Children over 12 years of age weighing less than 40 kg: 5 to 7 mg/kg per day in 24 hours, divided into 4 doses every 6 hours.
Macrofurin Side Effects
The use of macrofurin® can cause in certain patients some of the following adverse reactions :
- Possible allergic reactions due to contact with any component of the formula.
- Fever , cough and chest pain.
- Hepatitis risk.
- Vomiting , diarrhea , and nausea may occur .
- In isolated cases, deterioration of respiratory function may occur.
- Steven Johnson syndrome.
- Hematologic disorders such as hemolytic anemia and eosinophilia.
Important: If any of these symptoms appear during treatment with macrofurin®, please discontinue use and inform your doctor .
Contraindications and warnings of macrofurin
Treatment with macrofurin® is contraindicated in the following cases:
- Hypersensitivity to any of the components of the formula.
- In people with kidney failure.
- During the period of pregnancy or lactation .
- In children under 12 years of age.
You should know: Before starting treatment with macrofurin®, it is advisable to provide all the information about your health history to your doctor.
Avoid if you have:
- Kidney deterioration problems.
- Anuria (lack of urine output) or oliguria (decreased urine output).
Warnings:
- Follow the instructions of your treating physician during treatment with macrofurin®.
- This pharmaceutical product must be administered through prescription or medical prescription.
- Macrofurin® in capsules should be administered with food for better absorption.
- Nitrofurantoin-based drugs, such as macrofurin®, can cause drug interactions if they are combined with other drugs for other diseases, which can be detrimental to the patient’s health.
- Keep this medicine out of the reach of children.
- Store in a cool dry place.
University Professional in the area of Human Resources, Postgraduate in Occupational Health and Hygiene of the Work Environment, 14 years of experience in the area of health. Interested in topics of Psychology, Occupational Health, and General Medicine.