What is loxonin?

Loxonin® is a synthetic medication that contains loxoprofen sodium (1) as active ingredient , a chemical compound derived from propionic acid. 

To highlight: This drug belongs to the line of drugs with an analgesic, anti-inflammatory and antipyretic effect for the relief of painful inflammatory processes derived from multiple causes. It is manufactured by the company named Siegfried Rhein, SA de CV (2)

What is loxonin used for?

  • Due to its analgesic and anti-inflammatory properties, loxonin® is used to treat various osteomuscular and joint ailments derived from different pathologies of traumatic origin.
  • It is used to treat: 
    • Osteoarthritis.
    • Rheumatoid arthritis.
    • Scapulohumeral periarthritis.
    • Musculoskeletal inflammatory processes of the neck , shoulder, arms and low back pain.
    • Acute inflammatory processes of the respiratory tract.
    • Pain and inflammation of post-surgical, post-traumatic and post-extraction processes. (3)

Dosage and routes of administration of loxonin

The presentation of loxonin® is in a box of 10 tablets with 60 mg of loxoprofen and a box with 20 tablets of 60 mg of the same component. The route of administration is oral and the dose for information may be as follows:

  • Adults and children over 12 years: 1 tablet every 8 hours per day or as recommended by your doctor.

loxonin side effects

Treatment with loxonin® may cause some of the following adverse effects in certain patients :

  • Possible adverse reactions from contact with any of the components of the formula.
  • Rash and hives.
  • Drowsiness and headache.
  • In rare cases peptic ulcer , hemolytic  anemia and mucocutaneous syndrome.
  • Acute renal failure and congestive heart failure.
  • In isolated cases interstitial pneumonia, gastrointestinal bleeding and gastrointestinal perforation. 
  • Liver function disorders, asthmatic attack and aseptic meningitis.
  • Its chronic use can cause stenosis and/or obstruction of the small intestine and/or large intestine or ulcer of the small intestine and/or large intestine.
  • Episodes of abdominal pain, nausea, and vomiting may appear .

Important: If during treatment with loxonin ® appear any of these symptoms or another not included in the list, please discontinue use and notify your doctor .

Contraindications and warnings of loxonin

The use of loxonin® is contraindicated in the following cases:

  • Hypersensitivity to any of the components of loxonin®.
  • Patients with peptic ulcer.
  • Patients under 12 years of age.
  • Patients with severe hematological disorders.
  • Patients with severe renal insufficiency.
  • Patients with severe hepatic impairment.
  • People with severe heart failure.
  • Women in the last trimester of pregnancy.
  • During the breastfeeding period .

You should know: Provide all information about your medical history to your doctor, before starting treatment with loxonin®.

Avoid if you have:

  • NSAID-induced asthma.
  • Gastric ulcer associated with prolonged intake of NSAIDs.
  • History of peptic ulcer.
  • History of blood disorders.
  • Ulcerative colitis.
  • Crohn’s disease.


  • Pharmaceutical products such as loxonin® must be administered with a prescription or medical prescription.
  • During treatment with this medicine, the consumption of alcoholic beverages should be avoided.
  • Avoid taking oral anticoagulants and benzothiazide diuretics during treatment with loxonin®. 
  • This drug should be kept out of the reach of children.
  • Keep this pharmaceutical product stored in a dry and cool place.

Leave a Reply

Your email address will not be published. Required fields are marked *