What is histofil?

Histofil®is the brand name of a pharmaceutical medicinethat usescholecalciferol (Vitamin D3), a chemical compound belonging to the line of medicines called vitamin D analogues, withan effect on bone mineralization and calcium metabolism.

To highlight: This pharmaceutical product is made by the company namedPRODUCTOS MEDIX, S.A. de C.V. (1)

What is histofil for?

  • Thanks to the mechanism of action of its active ingredient, histophyll®facilitates the digestive absorption of calcium containedin the diet and participates in bone formation and restoration as well as helping in theprevention of several diseases of the bone system(2)
  • It is used to treat:
    • VitaminD deficiencies due to hypocalcemia and osteoporosis type I and II.
    • Vitamin D deficiencies from hyperparathyroidism with bone disease, rickets and osteomalacia.
    • Vitamin D deficiencies due to obesity, diabetesmellitus, nutritional status and malabsorption.
    • Patients at significant risk of vitamin D deficiency.(3)

Histofil dosage and routes of administration

The presentation of histofil® is in tabletsthat contain cholecalciferol (Vitamin D3) 4,000 IU. The administrationis orally and the dosage as a reference can be as follows:

  • Adults: One 4,000 IU tablet once a day.

Histofil Side Effects

Clinical data indicate that therapeutic treatment with histofil® may cause some of the following adverse effects in a certain patient population:

  • Possible allergic reactions due to contact with any chemical component of the medication.
  • Gastrointestinal complaints such as nausea, Vomiting , diarrhea ,  constipation , anorexia, pancreatitis, and lipid abnormalities.
  • Polyuria, polydipsia, urolithiasis, proteinuria and kidney damage.
  • Decreased levels of high-density lipoproteins and increases in low-density lipoproteins.
  • Nephrocalcinosis and nephrolithiasis.
  • Hypertension and possibly arrhythmias.
  • Headache and psychotic symptomatology.

Important: If during treatment with this supplement any of these symptoms or another not described arise, please stop using it and consult your doctor .

Contraindications and warnings of histofil

The use of histofil® is contraindicated in the following cases:

  • Patient hypersensitivity to any of the components of the formula.
  • Patients with hypercalcaemia and hypercalciuria, due to risk of exacerbation.
  • Patients with hypervitaminosis D.
  • People who suffer from calcium lithiasis.
  • Patients with osteodystrophy with hyperphosphatemia.
  • In severe renal insufficiency.

You should know: Provide all the information regarding your health history to your doctor, before starting treatment with this medicine.

Avoid if you have:

  • History of hypersensitivity to cholecalciferol, ergocalciferol, or any of the vitamin D metabolites.

Warnings:

  • Pharmaceutical products such as histofil® must be administered with a prescription or medical prescription.
  • Follow your doctor’s instructions during treatment with this supplement.
  • Do not exceed the dose indicated by your doctor.
  • Caution should be exercised in the administration of this drug in people with atherosclerosis.
  • Keep this product out of the reach of children.
  • Store in a cool dry place.

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