What is flunarizine?

Flunarizine is a synthetic medicineclassified as an active ingredient, which belongs to the group of medicines with calcium channel blocking properties, witheffect on certain conditions in the body(1)

What is flunarizine for?

  • Flunarizine thanks to its mechanism of action, prevents the overload of calcium in the blood vessels, preventing the contraction of the muscles and producing vasodilation.
  • It is used to treat:
    • The states of arteriovenous pain syndrome and prophylaxis of classicmigrainewith severe and frequent attacks. (2)
    • Circulatory deficiency in the extremities (ulcers, varicose states).
    • I am dizzy in the vestibule.
    • Night cramps.
    • cold extremities.
    • Intermittent claudication.
    • Raynaud’s syndrome.

Dosage and routes of administration of flunarizine

Flunarizine is usually sold in 5 and 10 mg capsulestag. The administrationis orally and the dosage as a reference, can be the following:

  • Patients under 65 years of age: The indicated dose is one 10 mg tablet once a day and in patients over 65 years of age, a dose of 5 mg per day.

What products contain flunarizine?

Some of the medicines that contain flunarizine are:

  • Buflin®
  • Fasolan®
  • Nafliuryl®
  • Sibelium®


  • Buflin® is the trade name of a synthetic medicine that contains flunarizine as an active ingredient in a concentration of 10 mg.
  • It is used in the prophylaxis of migraine in patients with severe and frequent attacks.


  • Fasolan® is a synthetic brand-name drug that uses flunarizine as an active substance in a concentration of 10 mg.
  • It is used as an aid in the prophylaxis of common migraine or classic migraine.


  • Nafliuryl® is a synthetically manufactured medicine that uses flunarizine as the active ingredient and comes in 5 mg tablets.
  • It is indicated in migraine syndrome , arteriovenous pain, circulatory deficiency.


  • Sibelium® is a drug with calcium channel blocking properties, which uses flunarizine as an active ingredient.
  • It is indicated in the prevention of migraine and to relieve the symptoms of vestibular vertigo.

Flunarizine Side Effects

Clinical data indicate that treatment with flunarizine may cause, in a certain patient population , some of the following adverse effects:

  • Adverse reactions due to patient contact with any of the components of the formula.
  • Increased body weight and/or increased appetite.
  • Drowsiness, depression and/or fatigue.
  • Extrapyramidal reaction, parkinsonism.
  • Rigidity, orofacial dyskinesia, tremors.

Important: If any of these symptoms or other symptoms not included in this list appear during treatment with flunarizine, please discontinue use and notify your doctor .

Contraindications and warnings of flunarizine

The use of flunarizine is contraindicated in the following circumstances:

  • Hypersensitivity to any of the components of the formula or to cinnarizine .
  • Patients with recent cerebral hemorrhage and extrapyramidal symptoms.
  • in patients with Parkinson’s disease.
  • During the first trimester of pregnancy.
  • During breastfeeding .

You should know: Before starting treatment with this drug, provide all the information regarding your medical history to your doctor.

Avoid it if you have:

  • History of hypersensitivity to flunarizine or cinnarizine.
  • History of depressive illnesses.
  • Pre-existing symptoms of Parkinson’s or other conditions.
  • Glaucoma, prostatic hypertrophy or liver failure.


  • Products such as flunarizine must be administered with a prescription or prescription.
  • It should be noted that a dose adjustment should be made in cases of renal insufficiency and in the elderly.
  • Concomitant use of flunarizine with other drugs has caused a decrease in its plasma levels.
  • Keep this medicine out of the reach of children.
  • Store this product in a cool, dry place.

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