What is the phasiclor?
Fasiclor® is the trademark of a semi-synthetic medicine, which uses cefaclor (1) as its active principle , a chemical compound belonging to the line of second-generation cephalosporin antibiotic medicines, with an effect on bacteria that cause infections of the respiratory tract, skin and urinary tract .
To highlight: This pharmaceutical product is produced by the company named PRODUCTOS MAVER, SA de CV (2)
What is the fasichlor used for?
- Thanks to the mechanism of action of its active ingredient, fasiclor® selectively inhibits the synthesis of the bacterial cell wall, causing cell lysis, making it a powerful bactericide, eliminating a broad spectrum of microorganisms that cause various infections .
- It is used to treat:
- Lower respiratory tract infections such as bronchitis , acute exacerbations of chronic bronchitis, and pneumonias caused by S. pneumoniae, H. influenzae, S. pyogenes . (3)
- Upper respiratory tract infections including pharyngitis and tonsillitis.
- Infections of the skin and subcutaneous tissue.
- otitis media.
- Acute and chronic sinusitis.
- Urinary tract infections such as pyelonephritis, cystitis, and urethritis caused by E. coli, Proteus mirabilis .
- Gonococcal urethritis.
Dosage and routes of administration of fasiclor
Fasiclor® is presented in a box with a 125 mg/5 ml, 250 mg/5 ml and 375 mg/5 ml bottle containing cefaclor monohydrate. The administration of this medicine is orally and the dosage as a reference can be the following:
- Adults: The recommended dose is 250 mg every 8 hours and can be increased up to 500 mg, according to the severity of the disease and the treating physician’s judgment.
- Children: The recommended dose is 20 mg/kg/day in divided doses every 3 times a day, which can be modified up to 40 mg/kg/day at the discretion of the doctor.
Note: The total daily dose should not exceed 4 g/day for a maximum period of 28 days.
Fasichlor Side Effects
Data from clinical studies indicate that treatment with fasiclor® may cause, in a certain patient population , some of the following adverse effects:
- Possible allergic reactions due to patient contact with any component of the formula.
- Cholestatic jaundice , abnormal liver function tests, and erythema multiforme.
- Pseudomembranous colitis, diarrhea , nausea, and vomiting .
- Agranulocytosis, eosinophilia, hemolytic anemia , neutropenia, and thrombocytopenia.
- Stevens-Johnson syndrome , toxic epidermal necrolysis, and urticaria.
- Angioedema, arthralgia and arthritis.
- Fever and moniliasis.
Important: If during treatment with fasiclor® the patient suffers from any of these symptoms or another not described, please stop using it and notify your doctor .
Fasichlor contraindications and warnings
The use of fasiclor® is contraindicated in the following circumstances:
- Patient hypersensitivity to the components of the formula or to the group of cephalosporins.
- During the pregnancy period.
- During breastfeeding .
You should know: Before starting treatment with this drug, the patient must provide his doctor with all the information about his health history .
Avoid if you have:
- History of hypersensitivity to cefaclor or cephalosporins.
Warnings:
- Pharmaceutical products such as fasiclor®, must be administered with prescription or medical prescription.
- Do not exceed the dose recommended by your doctor.
- Follow your doctor’s instructions during treatment with this medicine.
- This product does not require dose adjustment in patients with renal failure.
- Keep this drug out of the reach of children.

University Professional in the area of Human Resources, Postgraduate in Occupational Health and Hygiene of the Work Environment, 14 years of experience in the area of health. Interested in topics of Psychology, Occupational Health, and General Medicine.