What is the phasiclor?

Fasiclor® is the trademark of a semi-synthetic medicine, which uses cefaclor (1) as its active principle , a chemical compound belonging to the line of second-generation cephalosporin antibiotic medicines, with an effect on bacteria that cause infections of the respiratory tract, skin and urinary tract .

To highlight: This pharmaceutical product is produced by the company named PRODUCTOS MAVER, SA de CV (2)

What is the fasichlor used for?

  • Thanks to the mechanism of action of its active ingredient, fasiclor® selectively inhibits the synthesis of the bacterial cell wall, causing cell lysis, making it a powerful bactericide, eliminating a broad spectrum of microorganisms that cause various infections .  
  • It is used to treat: 
    • Lower respiratory tract infections such as bronchitis , acute exacerbations of chronic bronchitis, and pneumonias caused by S. pneumoniae, H. influenzae, S. pyogenes . (3)
    • Upper respiratory tract infections including pharyngitis and tonsillitis.
    • Infections of the skin and subcutaneous tissue.
    • otitis media.
    • Acute and chronic sinusitis.
    • Urinary tract infections such as pyelonephritis, cystitis, and urethritis caused by E. coli, Proteus mirabilis .
    • Gonococcal urethritis.

Dosage and routes of administration of fasiclor

Fasiclor® is presented in a box with a 125 mg/5 ml, 250 mg/5 ml and 375 mg/5 ml bottle containing cefaclor monohydrate. The administration of this medicine is orally and the dosage as a reference can be the following:

  • Adults: The recommended dose is 250 mg every 8 hours and can be increased up to 500 mg, according to the severity of the disease and the treating physician’s judgment.
  • Children: The recommended dose is 20 mg/kg/day in divided doses every 3 times a day, which can be modified up to 40 mg/kg/day at the discretion of the doctor.

Note: The total daily dose should not exceed 4 g/day for a maximum period of 28 days.

Fasichlor Side Effects

Data from clinical studies indicate that treatment with fasiclor® may cause, in a certain patient population , some of the following adverse effects:

  • Possible allergic reactions due to patient contact with any component of the formula.
  • Cholestatic jaundice , abnormal liver function tests, and erythema multiforme.
  • Pseudomembranous colitis, diarrhea , nausea, and vomiting .
  • Agranulocytosis, eosinophilia, hemolytic anemia , neutropenia, and thrombocytopenia.
  • Stevens-Johnson syndrome , toxic epidermal necrolysis, and urticaria.
  • Angioedema, arthralgia and arthritis. 
  • Fever and moniliasis.

Important: If during treatment with fasiclor® the patient suffers from any of these symptoms or another not described, please stop using it and notify your doctor .

Fasichlor contraindications and warnings

The use of fasiclor® is contraindicated in the following circumstances:

  • Patient hypersensitivity to the components of the formula or to the group of cephalosporins.
  • During the pregnancy period.
  • During breastfeeding .

You should know: Before starting treatment with this drug, the patient must provide his doctor with all the information about his health history .

Avoid if you have:

  • History of hypersensitivity to cefaclor or cephalosporins.

Warnings:

  • Pharmaceutical products such as fasiclor®, must be administered with prescription or medical prescription.
  • Do not exceed the dose recommended by your doctor.
  • Follow your doctor’s instructions during treatment with this medicine.
  • This product does not require dose adjustment in patients with renal failure.
  • Keep this drug out of the reach of children.

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