What is diosmin?

Diosmin is a chemical substance considered as an active principle by medical science, belonging to the line of medicines with venotonic properties with an effect on the body’s circulatory system . (1)

What is diosmin used for?

  • Diosmin is a medication that, thanks to its mechanism of action, exerts a double action on the venous return system by increasing parietal tonicity and has an antistatic action at the level of the microcirculation of blood vessels, normalizing and reinforcing permeability and resistance. capillary . (two)
  • It is used to treat: 
    • Patients with varicose veins , varicose syndrome and venous insufficiency. 
    • Phlebalgia and heaviness in the legs.
    • Static leg edema, postphlebitic sequelae and pre-ulcer states. 
    • Hemorrhoids and capillary fragility hemorrhages.

Dosage and routes of administration of diosmin

The presentation of diosmin can be, according to the manufacturer’s laboratory , in a box with 15, 20, 30 or 60 tablets or tablets, which contain 450 mg of diosmin, generally accompanied by 50 mg of hesperidin (500 mg per tablet). The administration of this medication is orally and its dosage, for information purposes, may be as follows: 

  • Varicose veins and hemorrhoids: A dose of 2 tablets together per day is recommended, until indicated by the treating physician. 
  • Hemorrhoidal crisis: It is recommended to start therapy with an initial dose of 6 tablets and then adjust the dose, according to the doctor’s recommendation.

What products contain diosmin?

Some of the medicines that contain diosmin are:

  • Espidorm®
  • Daflon®
  • Elatec®
  • Flausiver®

Espidorm®

  • Espidorm® is a drug manufactured by pharmaceuticals, which contains the combination of diosmin and hesperidin in its formulation.
  • It is indicated for the treatment of symptoms related to mild venous insufficiency in adults.

Daflon®

  • Daflon® is a venotonic medication, which uses the combination of two active ingredients that are diosmin and hesperidin, which comes in tablet form. 
  • It is used in the treatment to increase the tone of the veins and the resistance of the capillaries.

Vasculflow®

  • Vasculflow® is a medication in the form of tablets, which uses the combination of calcium dobesilate, diosmin and hesperidin.
  • It is indicated for the treatment of acute hemorrhoidal crises and functional crises of hemorrhoids.
  • If you want to know more about this medicine, see Vasculflow: What is it and what is it for? .

Flausiver®

  • Flausiver® is a phlebotropic medication, which has a mixture of two drugs such as diosmin and hesperidin.
  • It is indicated in the treatment of chronic venous insufficiency problems .
  • If you want to know more about this medicine, see What is the flausiver and what is it for? .

Diosmin Side Effects

Data from clinical studies have indicated that the use of diosmin may cause, in a certain group of patients , some of the following adverse effects: 

  • Allergic manifestations due to patient contact with any chemical component of the formula.
  • Diarrhea , indigestion , nausea, vomiting , and colitis .
  • Dizziness, headache and malaise.  
  • Skin reactions such as rash, pruritus and hives.
  • Abdominal pain, isolated edema of the face, lips, and eyelids.

Important: If the patient manifests any of these adverse reactions or another not described, please discontinue use and consult your doctor .

Contraindications and warnings of diosmin.

The use of diosmin is contraindicated in any of the following cases:

  • Patient hypersensitivity to any of the components of the formula.
  • In patients under 18 years of age.
  • In women during the period of pregnancy.
  • During breastfeeding .

To highlight: Provide all available information regarding your health history to your doctor, before starting treatment with this drug.

Avoid if you have:

  • History of hypersensitivity to diosmin or allergy to flavonoids.
  • Medication with other drugs for other pathologies, without the prior consultation of the doctor.

Warnings:

  • Pharmaceutical products such as diosmin, must be administered with prescription or medical prescription.
  • Although studies indicate that this medicine does not have any harmful effects, it is necessary to follow your doctor’s instructions.
  • Do not exceed recommended dose.
  • Avoid prolonged use without medical supervision.
  • Keep this product out of the reach of children.

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