Brunadol: What is it and what is it for?

What is brunadol?

Brunadol® is the trademark of a combined medicine that uses paracetamolandnaproxen as active ingredients, chemical compounds that belong to the line of analgesic, antipyretic and anti-inflammatory drugs, witheffect on different painful processes in the body.

To highlight: This pharmaceutical product is made in Mexico by the company namedBruluagsa, S.A. de C.V. (1)

What is brunadol for?

• Thanks to the combination of its active components (paracetamol/naproxen), brunadol®produces an analgesic, non-narcotic antipyretic effectwith selective action in thecentral nervous system, in addition to inhibiting the synthesis of prostaglandins that cause pain and inflammation. Through this mechanism of action, it is possible to mitigate the processes of pain and inflammation ofvarious etiologies in a longer way.
• It is used to treat:
  • Pain andfeveron antibiotic therapy inrespiratory tract infections (as an adjunct). (2)
  • Pain and inflammation of otalgias, in postoperative and postpartum, musculoskeletal pain. (3)
  • Pain and inflammation from pharyngeal surgery,dentalandtraumatic processes.

Dosage and routes of administration of brunadol

The commercial presentation of brunadol® is in tabletscontaining naproxen sodium 275 mg and paracetamol 300 mg; It also comesin suspension inbottle of 100 and 120 ml with naproxen 2.5 gr and paracetamol 2 gr. The route of administration in both cases is oral and the posology as a referential may be as follows:

• Tablets: Treatment can start with 2 tablets and then one tablet every 6 to 8 hours, until symptoms are controlled.
• Suspension: In children 2 to 3 years of age, administer half a teaspoon of 5 ml every 8 hours and for children over 3 years of age, administer 5 ml every 8 hours.

side effects of brunadol

The therapeutic treatment with brunadol® Can cause some of the following adverse effects in a certain patient population:

• Possible allergic reactions due to contact with any component of the formula.
• Abdominal discomfort, vomiting , nausea and epigastric discomfort.
• Colitis , gastrointestinal ulcerations and ulcerative stomatitis.
• Vertigo and peripheral edema.
• Aseptic meningitis, agranulocytosis, thrombocytopenia.
• Hemolytic and aplastic anemia, erythema multiforme.
• Fulminant hepatitis from jaundice .
• Inability to concentrate, insomnia .
• Skin rashes, dermatitis , hives, and mucosal lesions.

Important: If during treatment with this drug the patient experiences any of these symptoms or another not included in the list, please stop using it and consult your doctor .

Contraindications and warnings of brunadol

The use of brunadol® is contraindicated in the following circumstances:

• Patient hypersensitivity to any of the components of the formula or to NSAID medications such as acetylsalicylic acid .
• Patients with hepatic insufficiency.
• People with oral anticoagulant treatment.
• Patients suffering from kidney failure.
• During the pregnancy period.
• During breastfeeding .
• In children under 12 years of age.

You should know: The patient must provide all the information about his health history to his doctor, before starting treatment with this drug.

Avoid if you have:

• History of hypersensitivity to any of the components of the formula or to NSAIDs.
• Agranulocytopenia, duodenal ulcer , acute gastritis and anemia.

Warnings:

• Pharmaceutical products such as brunadol® must be administered with a prescription or prescription.
• Do not use this medication for more than 10 continuous days.
• Keep this product out of the reach of children.
• Do not exceed the dose recommended by your doctor.
• Store in a dry and cool place.