What is antalgin?

Antalgin® is a medication that belongs to the line of non-steroidal anti -inflammatory drugs (NSAIDs), which uses sodium naproxen as an active ingredient , a chemical compound with analgesic and anti-inflammatory effects .

To be highlighted: antalgin® is commercially manufactured by the company named ATNAHS PHARMA NETHERLANDS BV .

What is antalgin used for?

  • Thanks to its mechanism of action, antalgin® inhibits the synthesis of prostaglandins and thromboxanes , by blocking the action of the enzyme cyclooxygenase, thus reducing inflammation and, consequently, helping to treat pain.
  • It is used to treat:
    • The painful symptoms of primary dysmenorrhea (pains associated with menstruation).
    • Primary and secondary menorrhagia.
    • The painful processes of osteoarthritis , rheumatoid arthritis (chronic joint disorder), ankylosing spondylitis in the spine and acute episodes of gout.
    • Acute migraine attacks .
    • The inflammation, pain, and fever that accompany common respiratory infections .

Dosage and routes of administration of antalgin

Antalgin® is presented as extended-release film-coated tablets containing 550 mg naproxen sodium, equivalent to 500 mg naproxen. The route of administration is oral and the indicative dosage is as follows:

  • Rheumatoid arthritis, osteoarthritis and ankylosing spondylitis: The recommended daily dose is 1100 mg of antalgin®, twice a day every 12 hours.
  • Acute attacks of gout: The recommended initial dose is 825 mg naproxen sodium, followed by 275 mg antalgin® every 8 hours.
  • Migraine: 825 mg of antalgin® taken as a single dose at the first symptoms and after half an hour another dose of 275 mg.
  • Dysmenorrhea: Antalgin® 550 mg taken as a single dose, followed by 275 mg every 6-8 hours.

antalgin side effects

Therapeutic treatment with antalgin® can cause some of the following adverse effects in certain patients :

  • Possible allergic reactions due to contact with any component of the formula.
  • Gastrointestinal bleeding, ulcers and perforations.
  • Risk of atherothrombotic events.
  • Events of exfoliative dermatitis , Stevens-Johnson syndrome , Crohn ‘s disease, and toxic epidermal necrolysis.
  • Altered kidney function, kidney failure, acute interstitial nephritis, hematuria, proteinuria, among others.

Important: If any of these symptoms or another not described in the list appear during treatment with antalgin®, please stop using it and consult your doctor.

Contraindications and warnings of antalgin

The use of antalgin® is contraindicated in the following cases:

  • Hypersensitivity to any component of the formula.
  • Patients with a history of bronchospasm, asthma, rhinitis, or urticaria associated with aspirin .
  • Patients with recurrent peptic ulcer.
  • Patients with gastrointestinal bleeding or perforation.
  • People with severe heart failure.
  • Women during the third trimester of pregnancy.
  • Patients with severe hepatic or renal insufficiency.
  • Patients with ulcerative colitis.

You should know: Give your doctor all the information about your health history, before starting treatment with antalgin®.

Avoid if you have:

  • History of allergies to NSAIDs.
  • Ulcer background.
  • History of hypertension and/or heart failure.
  • Uncontrolled hypertension.
  • History of liver or kidney failure.
  • A history of stroke problems, or you think you might be at risk for these conditions without consulting your doctor.


  • Pharmaceutical products such as antalgin® must be administered with a prescription or prescription.
  • Do not administer this medication with other NSAID drugs.
  • This product is not recommended for children and adolescents under 16 years of age.
  • The supervision of a doctor is recommended, during the period of treatment with antalgin®.
  • Do not administer this medication in parallel with other drugs for other pathologies, without medical consent.
  • Keep this drug out of the reach of children.

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